Improving outcomes from eating disorders (EDs) is a shared priority among researchers, clinicians and people with lived experience of EDs. Clinical quality registries (CQRs) may be one route to achieving this improvement. These registries systematically collect data to evaluate the quality, safety and outcomes of care delivered across services. Registries can use natural variations in treatments to identify areas of best practice and areas requiring improvement. Large-scale longitudinal datasets can support data-driven precision treatment approaches. Benchmarking data and feedback mechanisms allow participating services, health system managers, and policy makers to learn from the registry and improve outcomes. CQRs are also bridging the research translation gap, by providing infrastructure and cost savings for real world clinical trials and implementation studies. This symposium aims to outline the current state of ED CQRs; possible benefits for quality improvement and clinical research; and areas of opportunity for international collaboration.
a. EDRS 2026 focuses on New Treatments and Services for Eating Disorders, reflecting the urgent need to move beyond current guidelines by integrating mechanistic science with therapeutic innovation. Despite advances in psychotherapy and service delivery, many patients continue to experience incomplete response, relapse, and persistent medical and psychiatric morbidity. This symposium brings together leading investigators to examine emerging biological, nutritional, and neuromodulatory interventions that bridge behavior and neurobiology. Dr. Aaron Keshen (Chair) will open by outlining the rationale for innovative biological approaches in eating disorder care, emphasizing how advances in neurobiology may inform next-generation interventions. He will also highlight recent work on glucagon-like peptide-1 receptor agonists, including an international Delphi-based consensus initiative examining potential clinical applications, key risks, and resulting clinical and research recommendations.
Working across the age divide: Treatment innovations for adolescents and emerging adults with anorexia nervosa
Chairs: Beate Herpertz-Dahlmann, Aachen, Germany & Andreas Karwautz, Vienna, Austria
Anorexia nervosa (AN) is a serious eating disorder requiring timely, evidence-based, and developmentally appropriate interventions. Adolescence and emerging adulthood present specific treatment challenges, including the transition between child and adult services, the role of caregivers, persistent illness despite first-line interventions, and decisions regarding the optimal treatment setting. This symposium brings together four complementary studies exploring innovations in psychological treatment, family involvement, neuromodulation, and service delivery.
The first presentation examines the efficacy of the Maudsley Model of Anorexia Nervosa Treatment for Adults (MANTRa), adapted for younger patients, compared with treatment as usual in 92 adolescents and young adults aged 13–21 years in Austria. Both groups improved, but MANTRa was associated with greater improvements in BMI and eating disorder psychopathology.
The second presentation explores adapted Family Therapy for Anorexia Nervosa in 30 emerging adults aged 18–25 years. Among the 28 treatment completers, 71.4% restored their weight to a BMI above 18.5 kg/m², and 85.7% were discharged to general practitioner care alone, providing preliminary support for extending family-based approaches into emerging adulthood.
The third presentation reports on the RaISE randomised, sham-controlled feasibility trial of intermittent theta burst stimulation for persistent AN. Of 57 participants randomised, 82.5% completed the intervention, with clinical, neurocognitive, and neuroimaging outcomes being evaluated.
Finally, a large multicentre randomised controlled trial comparing home treatment with continued inpatient care in 160 adolescent females found comparable expected body weight at one year, alongside lower eating disorder symptomatology, fewer psychiatric comorbidities, and lower treatment costs in the home treatment group.
Together, these studies highlight opportunities to improve AN care through specialised psychological interventions, developmentally flexible family involvement, innovative approaches for persistent illness, and alternatives to prolonged inpatient treatment. The symposium emphasises the importance of individualising treatment according to developmental stage, clinical complexity, family context, and care needs, while evaluating longer-term outcomes to inform clinical practice across the adolescent-to-adult transition.
The four presentations collectively challenge a one-size-fits-all approach to anorexia nervosa treatment. They suggest four complementary directions for advancing care:
The overarching theme is that effective treatment should be guided not only by chronological age or weight restoration, but also by developmental needs, family resources, illness persistence, psychiatric comorbidity, and the appropriate intensity and setting of care.